Pesquisa | Portal de Pesquisa da BVS

1.

ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P.

Kim, Ju Youn; Garcia-Carbonell, Ricard; Yamachika, Shinichiro; Zhao, Peng; Dhar, Debanjan; Loomba, Rohit; Kaufman, Randal J; Saltiel, Alan R; Karin, Michael.

Cell ; 175(1): 133-145.e15, 2018 09 20.

Artigo em Inglês | MEDLINE | ID: mdl-30220454

2.

TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue.

Zhao, Peng; Wong, Kai In; Sun, Xiaoli; Reilly, Shannon M; Uhm, Maeran; Liao, Zhongji; Skorobogatko, Yuliya; Saltiel, Alan R.

Cell ; 172(4): 731-743.e12, 2018 02 08.

Artigo em Inglês | MEDLINE | ID: mdl-29425491

3.

A futile approach to fighting obesity?

Reilly, Shannon M; Saltiel, Alan R.

Cell ; 163(3): 539-40, 2015 Oct 22.

Artigo em Inglês | MEDLINE | ID: mdl-26496598

4.

Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes.

Keinan, Omer; Valentine, Joseph M; Xiao, Haopeng; Mahata, Sushil K; Reilly, Shannon M; Abu-Odeh, Mohammad; Deluca, Julia H; Dadpey, Benyamin; Cho, Leslie; Pan, Austin; Yu, Ruth T; Dai, Yang; Liddle, Christopher; Downes, Michael; Evans, Ronald M; Lusis, Aldons J; Laakso, Markku; Chouchani, Edward T; Rydén, Mikael; Saltiel, Alan R.

Nature ; 599(7884): 296-301, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34707293

5.

Derepressing nuclear receptors for metabolic adaptation.

Saltiel, Alan R.

Cell ; 147(4): 717-8, 2011 Nov 11.

Artigo em Inglês | MEDLINE | ID: mdl-22078871

6.

Fishing out a sensor for anti-inflammatory oils.

Saltiel, Alan R.

Cell ; 142(5): 672-4, 2010 Sep 03.

Artigo em Inglês | MEDLINE | ID: mdl-20813253

7.

White, brown, and beige; type 2 immunity gets hot.

Uhm, Maeran; Saltiel, Alan R.

Immunity ; 42(1): 15-7, 2015 Jan 20.

Artigo em Inglês | MEDLINE | ID: mdl-25607455

8.

Regulation of glucose transport by insulin: traffic control of GLUT4.

Leto, Dara; Saltiel, Alan R.

Nat Rev Mol Cell Biol ; 13(6): 383-96, 2012 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-22617471

9.

The protein kinase IKKepsilon regulates energy balance in obese mice.

Chiang, Shian-Huey; Bazuine, Merlijn; Lumeng, Carey N; Geletka, Lynn M; Mowers, Jonathan; White, Nicole M; Ma, Jing-Tyan; Zhou, Jie; Qi, Nathan; Westcott, Dan; Delproposto, Jennifer B; Blackwell, Timothy S; Yull, Fiona E; Saltiel, Alan R.

Cell ; 138(5): 961-75, 2009 Sep 04.

Artigo em Inglês | MEDLINE | ID: mdl-19737522

10.

Bi-allelic Variants in RALGAPA1 Cause Profound Neurodevelopmental Disability, Muscular Hypotonia, Infantile Spasms, and Feeding Abnormalities.

Wagner, Matias; Skorobogatko, Yuliya; Pode-Shakked, Ben; Powell, Cynthia M; Alhaddad, Bader; Seibt, Annette; Barel, Ortal; Heimer, Gali; Hoffmann, Chen; Demmer, Laurie A; Perilla-Young, Yezmin; Remke, Marc; Wieczorek, Dagmar; Navaratnarajah, Tharsini; Lichtner, Peter; Klee, Dirk; Shamseldin, Hanan E; Al Mutairi, Fuad; Mayatepek, Ertan; Strom, Tim; Meitinger, Thomas; Alkuraya, Fowzan S; Anikster, Yair; Saltiel, Alan R; Distelmaier, Felix.

Am J Hum Genet ; 106(2): 246-255, 2020 02 06.

Artigo em Inglês | MEDLINE | ID: mdl-32004447

11.

Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion.

Martin, Timothy D; Chen, Xiao-Wei; Kaplan, Rebecca E W; Saltiel, Alan R; Walker, Cheryl L; Reiner, David J; Der, Channing J.

Mol Cell ; 53(2): 209-20, 2014 Jan 23.

Artigo em Inglês | MEDLINE | ID: mdl-24389102

12.

YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity.

Wang, Lirui; Mazagova, Magdalena; Pan, Chuyue; Yang, Song; Brandl, Katharina; Liu, Jun; Reilly, Shannon M; Wang, Yanhan; Miao, Zhaorui; Loomba, Rohit; Lu, Na; Guo, Qinglong; Liu, Jihua; Yu, Ruth T; Downes, Michael; Evans, Ronald M; Brenner, David A; Saltiel, Alan R; Beutler, Bruce; Schnabl, Bernd.

Proc Natl Acad Sci U S A ; 116(30): 15184-15193, 2019 07 23.

Artigo em Inglês | MEDLINE | ID: mdl-31289229

13.

From overnutrition to liver injury: AMP-activated protein kinase in nonalcoholic fatty liver diseases.

Zhao, Peng; Saltiel, Alan R.

J Biol Chem ; 295(34): 12279-12289, 2020 08 21.

Artigo em Inglês | MEDLINE | ID: mdl-32651233

14.

Countering inflammatory signals in obesity.

Reilly, Shannon M; Saltiel, Alan R.

Nat Immunol ; 15(5): 410-1, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24747704

15.

Inhibition of AMPK catabolic action by GSK3.

Suzuki, Tsukasa; Bridges, Dave; Nakada, Daisuke; Skiniotis, Georgios; Morrison, Sean J; Lin, Jiandie D; Saltiel, Alan R; Inoki, Ken.

Mol Cell ; 50(3): 407-19, 2013 May 09.

Artigo em Inglês | MEDLINE | ID: mdl-23623684

16.

RalA controls glucose homeostasis by regulating glucose uptake in brown fat.

Skorobogatko, Yuliya; Dragan, Morgan; Cordon, Claudia; Reilly, Shannon M; Hung, Chao-Wei; Xia, Wenmin; Zhao, Peng; Wallace, Martina; Lackey, Denise E; Chen, Xiao-Wei; Osborn, Olivia; Bogner-Strauss, Juliane G; Theodorescu, Dan; Metallo, Christian M; Olefsky, Jerrold M; Saltiel, Alan R.

Proc Natl Acad Sci U S A ; 115(30): 7819-7824, 2018 07 24.

Artigo em Inglês | MEDLINE | ID: mdl-29915037

17.

Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation.

Ichikawa, Takafumi; Kita, Masahiro; Matsui, Tsubasa S; Nagasato, Ayaka Ichikawa; Araki, Tomohiko; Chiang, Shian-Huey; Sezaki, Takuhito; Kimura, Yasuhisa; Ueda, Kazumitsu; Deguchi, Shinji; Saltiel, Alan R; Kioka, Noriyuki.

J Cell Sci ; 130(20): 3517-3531, 2017 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-28864765

18.

Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1-mediated p62/sequestosome 1 phosphorylation.

Cho, Chun-Seok; Park, Hwan-Woo; Ho, Allison; Semple, Ian A; Kim, Boyoung; Jang, Insook; Park, Haeli; Reilly, Shannon; Saltiel, Alan R; Lee, Jun Hee.

Hepatology ; 68(4): 1331-1346, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-29251796

19.

Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat, and human microsomes.

Gan, Xinmin; Wilson, Michael W; Beyett, Tyler S; Wen, Bo; Sun, Duxin; Larsen, Scott D; Tesmer, John J G; Saltiel, Alan R; Showalter, Hollis D.

J Labelled Comp Radiopharm ; 62(5): 202-208, 2019 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-30828860

20.

Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKÎµ and Reveal Mechanisms for Selective Inhibition.

Beyett, Tyler S; Gan, Xinmin; Reilly, Shannon M; Chang, Louise; Gomez, Andrew V; Saltiel, Alan R; Showalter, Hollis D; Tesmer, John J G.

Mol Pharmacol ; 94(4): 1210-1219, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-30082428

Portal de Pesquisa da BVS

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar: